Mimitin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMimitin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionMimitin Antibody: Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-κB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimul
ImmunogenImmunogen: Mimitin antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Mimitin. Buffer: Mimitin Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Mimitin; MMTN; B17.2L; mimitin; NDUFA12L; Mimitin; mitochondrial; Myc-induced mitochondrial protein; MMTN; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2], [NDUFAF2; NDUFAF2; MMTN; B17.2L; mimitin; NDUFA12L; NDUFA12L; B17.2L; MMTN]
Gene, Accession #[NDUFAF2], Gene ID: 91942, NCBI: NP_777549, UniProt: Q8N183
Catalog #MBS150314
Price$375
Order / More InfoMimitin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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