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Antigenic Specificity | VEGFA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VEGF121 is the second most abundant splice variant of VEGF-A (1,2). VEGF121 is produced by endothelial cells, macrophages, Tcells and other cell types. VEGF121 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability (1). VEGF121 expression is induced by hypoxia, inflammatory cytokines and through oncogene products in tumors (1-3). VEGF121 binds to VEGFR1 and VEGFR2 receptor tyrosine kinases (1). Binding of VEGF121 to VEGFR1 and VEGFR2 leads to activation of pathways involving PI3K/AKT, P38 MAPK, and FAK (1). VEGF plays a key role in tumor angiogenesis in many cancers (2). |
Immunogen | Immunogen: C term -peptide of human VEGFA |
Other Names | [VEGFA; VEGFA; VEGF; L VEGFA; Vascular permeability factor; VEGF A; MVCD1], [VEGFA; VEGFA; VPF; VEGF; MVCD1; VEGF; VEGF-A; VPF] |
Gene, Accession # | Gene ID: 7422, NCBI: NP_001020537.2, UniProt: P15692 |
Catalog # | MBS125912 |
Price | $200, $275, $430 |
Order / More Info | VEGFA Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Takahashi, H. and Shibuya, M. (2005) Clin Sci (Lond) 109, 227-41. 2. Neufeld, G. et al. (1999) FASEB J 13, 9-22. 3. Robinson, C.J. and Stringer, S.E. (2001) J Cell Sci 114, 853-65. |