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Antigenic Specificity | Aquaporin 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~28.8kDa. May detect larger glycosylated bands ~35-50kDa. Scientific Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 2 is the vasopressin-regulated water channel of the apical membrane of collecting duct cells. It is located in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes. When it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that cause AQP2 containing vesicles to fuse with the plasma membrane so the AQP2 can be used by the cell (3). Defects in AQP2 ar |
Immunogen | n/a |
Other Names | [ADH water channel; AQP 2; AQP CD; AQP-2; AQP-CD; AQP2; AQP2_HUMAN; AQPCD; Aquaporin 2 collecting duct; Aquaporin CD; Aquaporin-2; Aquaporin-CD; Aquaporin2; Aquaporine 2; Collecting duct water channel protein; MGC34501; Water channel aquaporin 2; Water channel protein for renal collecting duct; WCH CD; WCH-CD; WCHCD], [Aqp2; Aqp2; AQP-2; aquaporin-2; AQP-2; AQP-CD] |
Gene, Accession # | Gene ID: 25386, NCBI: NP_037041.2, UniProt: P34080 |
Catalog # | MBS805221 |
Price | $425 |
Order / More Info | Aquaporin 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Gonen T., Walz T. (2006) Q. Rev. Biophys. 39(4): 361- |