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Antigenic Specificity | AGR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Two isoforms of AGR2 exists as a result of alternative splicing event. AGR2 Antibody: AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). |
Immunogen | Immunogen: Rabbit polyclonal AGR2 antibody was raised against a 17 amino acid peptide near the amino terminus of human AGR2. Buffer: AGR2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [AGR2; AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116; AG2; UNQ515/PRO1030; Anterior gradient protein 2 homolog; HPC8; AG-2; anterior gradient 2 homolog (Xenopus laevis)], [AGR2; AGR2; AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116; AG2; AG-2; hAG-2] |
Gene, Accession # | [AGR2], Gene ID: 10551, NCBI: NP_006399, UniProt: O95994 |
Catalog # | MBS153577 |
Price | $375 |
Order / More Info | AGR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |