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Antigenic Specificity | CD127/IL7R (Marker of T-Reg Cells) |
Clone | [IL7R/2751] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG2c, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). |
Immunogen | Immunogen: Recombinant fragment of human CD127 protein (IL7R) (around aa 21-236) (exact sequence is proprietary) Positive Control: K562, HeLa, Daudi or Jurkat Cells. Tonsil, Lymph Node or Spleen |
Other Names | [CD127; IL-7 receptor subunit alpha; IL-7R-alpha; IL7R; IL7RA; IL7R alpha; ILRA; Interleukin 7 receptor alpha chain; Interleukin 7 receptor] |
Gene, Accession # | [IL7R], Gene ID: 3575, NCBI: NP_002176.2, UniProt: P16871 |
Catalog # | MBS4380605 |
Price | $190, $340, $340 |
Order / More Info | CD127/IL7R (Marker of T-Reg Cells) Antibody from MYBIOSOURCE INC. |
Product Specific References | Weihong Liu et. al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4 T reg cells. J Exp Med. 2006 Jul 10; 203(7): 1701-1711. |