Human FAS (CD95) Blocking/Activating Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human FAS (CD95) Blocking/Activating |
| Clone | [NYRhFAS] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.5 mg, 1 mg |
| Concentration | 1 mg/ml in PBS (after reconstitution). |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: The Fas receptor (CD95) mediates apoptotic signaling by Fas-ligand expressed on the surface of other cells. The Fas-FasL interaction plays an important role in the immune system and lack of this system leads to autoimmunity, indicating that Fas-mediated apoptosis removes self-reactive lymphocytes. Fas signaling is also involved in immune surveillance to remove transformed cells and virus infected cells. Binding of FAS to oligimerized FasL on another cell activates apoptotic signaling through a cytoplasmic domain termed the death domain that interacts with signaling adaptors including FAF, FADD and DAX to activate the caspase proteolytic cascade. Caspase-8 and caspase-10 are first activated, to then cleave and activate downstre |
| Immunogen | Immunogen: Recombinant Human FAS. |
| Other Names | [FAS; FAS Blocking/Activating (CD95), Mouse Human; FASLG receptor; Apoptosis-mediating surface antigen FAS; Apo-1 antigen; CD95; Tumor necrosis factor receptor superfamily member 6 TNR6; APT1; FAS1; TNFRSF6], [FASN; FASN; FAS; OA-519; SDR27X1; FAS] |
| Gene, Accession # | [FAS], Gene ID: 2194, NCBI: NP_004095.4 |
| Catalog # | MBS140094 |
| Price | $305, $455 |
| Order / More Info | Human FAS (CD95) Blocking/Activating Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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