NR1D1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNR1D1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionTranscriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARTNL/BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. Recognizes two classes of DNA response elements within the promoter of its target gene
ImmunogenImmunogen: Recombinant human Nuclear receptor subfamily 1 group D member 1 protein
Other Names[Nuclear receptor subfamily 1 group D member 1; Rev-erbA-alpha; V-erbA-related protein 1; EAR-1; NR1D1; EAR1; HREV; THRAL]
Gene, Accession #[NR1D1], Gene ID: 9572, NCBI: NP_068370.1, UniProt: P20393
Catalog #MBS7044308
Price$160, $235
Order / More InfoNR1D1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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