Human Probable ATP-dependent RNA helicaseDDX58 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Probable ATP-dependent RNA helicaseDDX58 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | nnate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include: 5'-triphosphorylated ssRNA and dsRNA and short dsRNA (<1 kb in length). In addition to the 5'-triphosphate moiety, blunt-end base pairing at the 5'-end of the RNA is very essential. Overhangs at the non-triphosphorylated end of the dsRNA RNA have no major impact on its activity. A 3'overhang at the 5'triphosphate end decreases and any 5'overhang at the 5' triphosphate end abolishes its activity. Upon ligand binding it associates with mitochondria antiviral sig |
| Immunogen | Immunogen: Recombinant human Probable ATP-dependent RNA helicase DDX58 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-48929 / sc-48932 / sc-98911 |
| Other Names | [DEAD box protein 58 RIG-I-like receptor 1 Retinoic acid-inducible gene 1 protein Retinoic acid-inducible gene I protein DDX58], [DDX58; DDX58; RIGI; RIG-I; RLR-1; SGMRT2; RLR-1; RIG-1; RIG-I] |
| Gene, Accession # | [DDX58], Gene ID: 23586, NCBI: NP_055129.2, UniProt: O95786 |
| Catalog # | MBS1488203 |
| Price | $160, $235 |
| Order / More Info | Human Probable ATP-dependent RNA helicaseDDX58 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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