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Antigenic Specificity | PRKX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRKX antibody detects endogenous levels of total PRKX. Function: Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.Subunit Structure: Like other cAMP-dependent protein kinases, the inactive holoenzyme is probably composed of 2 PRK |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus Tissue Specificity: Widely expressed (at protein level). Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982. Predicted Cross Reactivity: Pig, Zebrafish, Horse, Sheep, Dog, Chicken, Xenopus Similarity: Pig (94%), Zebrafish (87%), Horse (94%), Sheep (93%), Dog (94%), Chicken (94%), Xenopus (94%) |
Other Names | [PKX1; PRKX; PRKX_HUMAN; Protein kinase PKX1; Serine/threonine-protein kinase PRKX] |
Gene, Accession # | [PRKX], Gene ID: 5613, NCBI: NP_005035.1, UniProt: P51817 |
Catalog # | MBS9605927 |
Price | $240, $280 |
Order / More Info | PRKX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |