Phospho-TSC2 Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Phospho-TSC2 Antibody Sampler Kit antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Phospho-TSC2 Antibody Sampler Kit |
| Clone | n/a |
| Host Species | n/a |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 kit |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity. In addition, tuberin inhibits the mammalian target of rapamycin (mTOR), which promotes inhibition of p70 S6 kinase, activation of eukaryotic initiation factor 4E binding protein 1 (4E-BP1, an inhibitor of translation initiation), and eventual inhib |
| Immunogen | n/a |
| Other Names | [Tsc2, partial; Tuberin; tuberin; TSC complex subunit 2; Tuberous sclerosis 2 protein homolog] |
| Gene, Accession # | [TSC2], Gene ID: 24855, NCBI: BAA25108.1 |
| Catalog # | MBS2550084 |
| Price | $220 |
| Order / More Info | Phospho-TSC2 Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies