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Antigenic Specificity | Cytochrome c |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space (1). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form (2). This event further triggers caspase-3 activation and eventually leads to apoptosis (3). |
Immunogen | Immunogen: Recombinant protein of human CYCS Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CYC; HCS; THC4] |
Gene, Accession # | [CYCS], Gene ID: 54205, NCBI: NP_061820.1, UniProt: P99999 |
Catalog # | MBS8500358 |
Price | $310 |
Order / More Info | Cytochrome c Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Schagger H.H. et al. (2002) Biochem. Biophys. Acta. 1555, 154-159. 2. Li, P. et al. (1997) Cell 91, 479-489. 3. Liu, X. et al. (1996) Cell 86, 147-157. |