IFNAR1/Beta R1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-IFNAR1/Beta R1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IFNAR1/Beta R1 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed: 2153461, PubMed: 7665574, PubMed: 10049744, PubMed: 14532120, PubMed: 15337770, PubMed: 21854986). Functions in general as heterodimer with IFNAR2 (PubMed: 7665574, PubMed: 10049744, PubMed: 21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (PubMed: 7665574, PubMed: 21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). |
| Immunogen | Immunogen: A synthesized peptide derived from human IFNAR1. Subcellular Localization: Isoform 1: Cell membrane; Single- pass type I membrane protein. Late endosome. Lysosome. Interferon binding triggers internalization of the receptor from the cell membrane into endosomes and then into lysosomes. Tissue Specificity: IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell |
| Other Names | [Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1; IFNAR], [IFNAR1; IFNAR1; AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; IFNAR; IFN-R-1; IFN-alpha/beta receptor 1; CRF2-1] |
| Gene, Accession # | [IFNAR1], Gene ID: 3454, NCBI: NP_000620.2, UniProt: P17181 |
| Catalog # | MBS179254 |
| Price | $160, $340, $340 |
| Order / More Info | IFNAR1/Beta R1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies