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Antigenic Specificity | H3F3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: H3F3A antibody detects endogenous levels of total H3F3A. Function: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA access |
Immunogen | Immunogen: A synthesized peptide derived from human H3F3A Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Expressed throughout the cell cycle independently of DNA synthesis. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Chicken (100%), Xenopus (100%) |
Other Names | [H3 histone family 3A; H3 histone family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3A; H3.3B; H33_HUMAN; H3F3; H3F3A; H3f3b; Histone H3.3; Histone H3.3Q; Histone H3.A; Histone H3.B; MGC87782; MGC87783] |
Gene, Accession # | [H3F3A], Gene ID: 3020, NCBI: NP_002098.1, UniProt: P84243 |
Catalog # | MBS9608419 |
Price | $240, $280 |
Order / More Info | H3F3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |