H3F3A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityH3F3A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: H3F3A antibody detects endogenous levels of total H3F3A. Function: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA access
ImmunogenImmunogen: A synthesized peptide derived from human H3F3A Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Expressed throughout the cell cycle independently of DNA synthesis. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Chicken (100%), Xenopus (100%)
Other Names[H3 histone family 3A; H3 histone family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3A; H3.3B; H33_HUMAN; H3F3; H3F3A; H3f3b; Histone H3.3; Histone H3.3Q; Histone H3.A; Histone H3.B; MGC87782; MGC87783]
Gene, Accession #[H3F3A], Gene ID: 3020, NCBI: NP_002098.1, UniProt: P84243
Catalog #MBS9608419
Price$240, $280
Order / More InfoH3F3A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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