LTbeta receptor, Mouse Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LTbeta receptor, Mouse |
| Clone | 5G11 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), FS, Immunoassay (IA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 5G11 reacts with the mouse lymphotoxin beta-receptor (LTbetaR), a member of the tumor necrosis factor (TNF) family. This receptor can be activated by its functional ligands lymphotoxin-alpha1-beta2 (LT-alpha1beta2) and LIGHT and is critically involved in controlling bacterial infections. In Mycobacterium infection, its role is related to bactericidal granuloma formation in the spleen, macrophage differentiation and the maintenance of the appropriate Th1/Th2 cytokine balance. In CMV infection, LTbetaR signaling induces the expression of IFN-beta in infected fibroblasts, resulting in viral stasis. LTbetaR plays an important role in lymphoid organogenesis and tumor development. The receptor is expre |
| Immunogen | n/a |
| Other Names | [lymphotoxin-beta; Lymphotoxin-beta; lymphotoxin-beta; TNF-C; LT-beta; lymphotoxin beta; tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3; lymphotoxin B; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3], [Ltb; Ltb; p33; Tnfc; LTbeta; Tnfsf3; AI662801; Tnfc; Tnfsf3; LT-beta; TNF-C] |
| Gene, Accession # | Gene ID: 16994, NCBI: NP_032544.1 |
| Catalog # | MBS584069 |
| Price | $720 |
| Order / More Info | LTbeta receptor, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hehlgans, T et al; Activation of the lymphotoxin-beta receptor induces NFkB-dependent interleukin-6 and MIP-2 secretion in mouse fibrosarcoma cells. Eur Cytokine Netw 2003, 14: 103 2. Lucas, R et al ; A role for lymphotoxin beta receptor in host defense against Mycobacterium bovis BCG infection. Eur J Immunol 1999, 29 : 4002 3. Banks, T et al : A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during Cytomegalovirus infection. J Immunol 2005, 174: 7217 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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