p53 (a.a. 371-380) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | p53 (a.a. 371-380) |
| Clone | [Pab122] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, monkey, hamster |
| Isotype | IgG2b |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | p53 is a 53 kDa transcription factor that can inhibit cell cycle progression or induce apoptosis in response to stress or DNA damage. Disruption of the p53 signalling pathway through various mechanisms is the most common alteration in human cancer occuring in over half of all tumors. The p53 protein is short lived and expressed at low levels in normal cells but accumulates and/or is activated in cells that have undergone genotoxic damage or oncogene activation. Many tumor derived and transformed cell lines express elevated levels of mutant p53 protein. Other genes also implicated in the downstream effects as a result of p53 activation are: p21WAF1, GADD45, 14-3-3, bax, Fas/APO1, KILLER/ DR5, Tsp1, IGF-BP3 and others. |
| Immunogen | Immunogen: Hybridoma produced by the fusion of splenocytes from immunized with full length mouse p53 protein and mouse myeloma cells. |
| Other Names | [apoptosis-inducing factor 2 isoform 2; Apoptosis-inducing factor 2; apoptosis-inducing factor 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; apoptosis-inducing factor-like mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death], [Aifm2; Aifm2; Amid; PRG3; 5430437E11Rik; D730001I10Rik; Amid] |
| Gene, Accession # | [p53], Gene ID: 71361, NCBI: NP_001034283.1, UniProt: Q8BUE4 |
| Catalog # | MBS395175 |
| Price | $340 |
| Order / More Info | p53 (a.a. 371-380) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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