Bit1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Bit1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bit1 Antibody: Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment. Bit1 (Bcl-2 inhibitor of transcription 1) was recently identified as being involved in this process. Bit1 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin-like enhancer of split (TLE) protein and induces caspase-independent apoptosis. Both AES and TLE proteins are transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. It has been suggested that Bit1-AES complexes turn off a |
| Immunogen | Immunogen: Bit1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human Bit1. Buffer: Bit1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [Bit1; BIT1; PTH2; CGI-147; BIT1; Peptidyl-tRNA hydrolase 2; mitochondrial; Bcl-2 inhibitor of transcription 1; PTH 2; peptidyl-tRNA hydrolase 2], [PTRH2; PTRH2; BIT1; PTH2; CFAP37; CGI-147; BIT1; PTH2; PTH 2] |
| Gene, Accession # | [PTRH2], Gene ID: 51651, NCBI: NP_057161, UniProt: Q9Y3E5 |
| Catalog # | MBS150626 |
| Price | $375 |
| Order / More Info | Bit1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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