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Antigenic Specificity | PRKAB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-termi |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human PRKAB2 (NP 005390.1). |
Other Names | [5'-AMP-activated protein kinase subunit beta-2; 5'-AMP-activated protein kinase subunit beta-2; 5'-AMP-activated protein kinase subunit beta-2; protein kinase AMP-activated non-catalytic subunit beta 2] |
Gene, Accession # | [PRKAB2], Gene ID: 5565, NCBI: O43741.1, UniProt: O43741 |
Catalog # | MBS8546464 |
Price | $280 |
Order / More Info | PRKAB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |