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Antigenic Specificity | IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) |
Clone | [1B1.3a] |
Host Species | Rat |
Reactive Species | mousedoes not react with human. |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Neutralization Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation. |
Immunogen | Immunogen: Purified recombinant extracellular region of Mouse IL10RA |
Other Names | [CD210 antigen; CDw210a; IBD28; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA IL10RIL-10R subunit alpha; interleukin 10 receptor; alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1] |
Gene, Accession # | [IL-10R1], Gene ID: 16154, NCBI: NP_032374.1, UniProt: Q61727 |
Catalog # | MBS4381528 |
Price | $190, $340, $340 |
Order / More Info | IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Vieira PL, et al. 2004. J. Immunol. 172:5986. (Neutralization). 2. Wang W, et al. 2004. FASEB J. 18:1043. (Neutralization) |