E-Cadherin (Cytoplasmic) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | E-Cadherin (Cytoplasmic) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, rat, mouse |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot, Immunocytochemistry, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This E-cadherin antibody detects a 120 kDa* protein in human A431 cells, and does not cross-react with Vecadherin or N-cadherin. Cadherins are transmembrane glycoproteins vital in calcium-dependent cell-cell adhesion during tissue differentiation. Cadherins cluster to form foci of homophilic binding units. A key determinant to the strength of the cadherin-mediated adhesion may be by the juxtamembrane region in cadherins. This region induces clustering and also binds to the protein p120 catenin. The cytoplasmic region is highly conserved in sequence and has been shown experimentally to regulate the cell-cell binding function of the extracellular domain of E-cadherin, possibly through interaction with the cytoskeleton. Many cadherins are regu |
| Immunogen | Immunogen: Clone (M168) was generated from a mouse recombinant E-Cadherin protein containing amino acids in the C-terminal region. This sequence ishighly conserved in human and rat E-cadherin. |
| Other Names | [Uvomorulin; Cadherin-1], [CDH1; CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; CD324; CDHE; UVO] |
| Gene, Accession # | Gene ID: 999, NCBI: P12830.3, UniProt: P12830 |
| Catalog # | MBS470009 |
| Price | $325 |
| Order / More Info | E-Cadherin (Cytoplasmic) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Takeichi, M. (1988) Development 102:639• Xu, Y. et al. (1997) J. Biol. Chem. 272(21):13463• Qi, J. et al. (2006) Mol. Biol. Cell 17(3):1261 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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