Human CD221: Low Endotoxin Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD221: Low Endotoxin antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human CD221: Low Endotoxin |
| Clone | [1H7] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Flow cytometry (FC/FACS), Functional Assays (FN), Immunohistology Paraffin*, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human CD221 antibody, clone 1H7 recognizes human CD221, a 155kD receptor tyrosine kinase, also known as Insulin-like growth factor I receptor (IGF-I Receptor). CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Clone 1H7 recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting (Li et al.1993). CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins. Clone 1H7 is reported to partically block binding of IGF-I and IGF-II to CD22 |
| Immunogen | Histology Positive Control Tissue: Pancreas, placenta Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [insulin-like growth factor 1 receptor isoform 1; Insulin-like growth factor 1 receptor; insulin-like growth factor 1 receptor; IGF-I receptor; insulin-like growth factor I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD_antigen: CD221Cleaved into the following 2 chains:Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain], [IGF1R; IGF1R; IGFR; CD221; IGFIR; JTK13; IGF-I receptor] |
| Gene, Accession # | [CD221], Gene ID: 3480, NCBI: NP_000866.1, UniProt: P08069 |
| Catalog # | MBS211237 |
| Price | $675 |
| Order / More Info | Human CD221: Low Endotoxin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies