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Antigenic Specificity | GPR77 (C-term), 297-325 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.29 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GPR77 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77. The anaphylatoxins C3a (see MIM 120700), C4a (see MIM120810), and C5a are cationic fragments generated during thecomplement cascade that participate in host defense. In the case ofinappropriate complement activation, anaphylatoxins may be involvedin autoimmunity and sepsis. C5L2 is coexpressed with the C5areceptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophilsand may modulate C5AR activity (Gerard et al., 2005 [PubMed16204243]). |
Immunogen | n/a |
Other Names | [C5a anaphylatoxin chemotactic receptor 2; Complement component 5a receptor 2; G-protein coupled receptor 77; C5AR2; C5L2; GPR77] |
Gene, Accession # | [C5AR2], Gene ID: 27202, NCBI: NP_001258678.1, UniProt: Q9P296 |
Catalog # | MBS9203546 |
Price | $165, $370 |
Order / More Info | GPR77 (C-term), 297-325 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bamberg, C.E., et al. J. Biol. Chem. 285(10):7633-7644(2010) Cui, W., et al. Mol. Immunol. 46(16):3207-3217(2009) Cui, W., et al. Mol. Immunol. 46(15):3086-3098(2009) Scola, A.M., et al. Mol. Immunol. 46(6):1149-1162(2009) Scola, A.M., et al. J. Biol. Chem. 282(6):3664-3671(2007) |