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Antigenic Specificity | ALDH1A3 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene. Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.Protein Function: Recognizes as substrates free retinal and cellular retinol-binding |
Immunogen | Immunogen: E Coli-derived human ALDH1A3 recombinant protein (Position: N37-K154). Human ALDH1A3 shares 89% and 87.3% amino acid (aa) sequence identity with mouse and rat ALDH1A3, respectively. Subcellular Localization: Cytoplasm. Tissue Specificity: Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney. |
Other Names | [Aldehyde dehydrogenase family 1 member A3; 1.2.1.5; Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; ALDH1A3; ALDH6] |
Gene, Accession # | [ALDH1A3], Gene ID: 220, NCBI: NP_000684.2, UniProt: P47895 |
Catalog # | MBS1750811 |
Price | $315 |
Order / More Info | ALDH1A3 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |