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Antigenic Specificity | NMDA Receptor, NR2B Subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse, human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.01 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~180k NR2B subunit of the NMDA receptor. Recognizes human, mouse and rat forms of the NR2B subunits of NMDAR. Immunolabeling is blocked by pre-adsorption of antibody with the fusion protein used to generate the antibody. No reactivity towards the NR2A and NR2C subunits. Affinity purified rabbit polyclonal antibody |
Immunogen | Antigen: Fusion protein from the C-terminus of the NR2B subunit of rat NMDA receptor. Immunogen Information: Fusion protein from the C-terminal region of the NR2B subunit. Immunogen Species: Rat |
Other Names | [glutamate receptor ionotropic, NMDA 2B; Glutamate receptor ionotropic, NMDA 2B; glutamate receptor ionotropic, NMDA 2B; NR2B; NMDAR2B; glutamate receptor, ionotropic, NMDA2B; N-methyl D-aspartate receptor subtype 2B; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B], [Grin2b; Grin2b; GluN2B; GluN2B; NMDAR2B; NR2B] |
Gene, Accession # | [GRIN2B], Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960 |
Catalog # | MBS502086 |
Price | $360 |
Order / More Info | NMDA Receptor, NR2B Subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | • Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD (2003) Tyrosine dephosphorylation and ethanol inhibition of N-methyl-D-aspartate receptor function. J Biol Chem 278:11020-11025.• Carroll RC, Zukin RS (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci 25:571-577.• Clayton DA, Grosshans DR, Browning MD (2002a) Aging and surface expression of hippocampal NMDA receptors. J Biol Chem 277:14367-14369.• Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD (2002b) A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J Neurosci 22:3628-3637.• Grosshans DR, Clayton DA, Coultrap SJ, Browning MD (2002) LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5:27-33. |