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Antigenic Specificity | ACHE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ACHE antibody detects endogenous levels of total ACHE. Description: Interacts with PRIMA1. The interaction with PRIMA1 is required to anchor it to the basal lamina of cells and organize into tetramers By similarity. Isoform H generates GPI-anchored dimers; disulfide linked. Isoform T generates multiple structures, ranging from monomers and dimers to collagen-tailed and hydrophobic-tailed forms, in which catalytic tetramers are associated with anchoring proteins that attach them to the basal lamina or to cell membranes.Function: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.Subunit Structure: Interacts wit |
Immunogen | Immunogen: A synthesized peptide derived from human ACHE Subcellular Location: Cell Membrane; Cell Junction > Synapse. Secreted. Cell Membrane and Nucleus. Only observed in apoptotic nuclei. Tissue Specificity: Isoform H is highly expressed in erythrocytes. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (89%), Xenopus (91%) |
Other Names | [ACEE; ACES_HUMAN; Acetylcholinesterase; AChE; Apoptosis related acetylcholinesterase; ARACHE; N ACHE; N-ACHE; YT; YT blood group] |
Gene, Accession # | [ACHE], Gene ID: 43, NCBI: NP_000656.1, UniProt: P22303 |
Catalog # | MBS9601447 |
Price | $240, $280 |
Order / More Info | ACHE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |