AKAP13 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKAP13
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: AKAP13 antibody detects endogenous levels of total AKAP13. Function: Scaffold protein that plays an important role in assembling signaling complexes downstream of several types of G protein-coupled receptors. Activates RHOA in response to signaling via G protein-coupled receptors via its function as Rho guanine nucleotide exchange factor (PubMed:11546812, PubMed:15229649, PubMed:23090968, PubMed:25186459, PubMed:24993829). May also activate other Rho family members (PubMed:11546812). Part of a kinase signaling complex that links ADRA1A and ADRA1B adrenergic receptor signaling to the activation of downstream p38 MAP kinases, such as MAPK11 and MAPK14 (PubMed:17537920, PubMed:23716597, PubMed:21224381). Part of a signaling comple
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cytoplasm; Cytoplasm. Nucleus and Membrane. Tissue Specificity: Detected in mammary gland (PubMed:9627117). Detected in heart (at protein level) (PubMed:11546812). Expressed as a 5.3 kb transcript in hematopoietic cells, skeletal muscle, lung, heart, estrogen-responsive reproductive tissues, including breast ductal epithelium. Also found in testis and breast cancer cell lines. Predominantly expressed as a 10 kb transcript in the heart and at
Other Names[A kinase (PRKA) anchor protein 13; A kinase anchor protein 13; A kinase anchoring protein; A-kinase anchor protein 13; AKAP 13; AKAP Lbc; AKAP-13; AKAP-Lbc; AKAP13; AKP13_HUMAN; ARHGEF13; Breast cancer nuclear receptor binding auxiliary protein; Breast cancer nuclear receptor-binding auxiliary protein; BRX; c lbc; FLJ11952; FLJ43341; Guanine nucleotide exchange factor Lbc; HA 3; HA3; Ht 31; Ht31; Human thyroid anchoring protein 31; Human thyroid-anchoring protein 31; LBC; LBC oncogene; Lymphoid blast crisis oncogene; Non oncogenic Rho GTPase specific GTP exchange factor; Non-oncogenic Rho GTPase-specific GTP exchange factor; p47; Protein kinase A anchoring protein 13; Protein kinase A-anchoring protein 13; PROTO LB; PROTO LBC]
Gene, Accession #[AKAP13], Gene ID: 11214, NCBI: NP_001257475.1, UniProt: Q12802
Catalog #MBS9604711
Price$240, $280
Order / More InfoAKAP13 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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