Bovine CD18 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Bovine CD18 |
| Clone | [BAQ30A] |
| Host Species | Mouse |
| Reactive Species | bovine, goat, sheep, bison, water buffalo, cat, dog, Alpaca, llama, human |
| Isotype | IgG1 |
| Format | supernatant |
| Size | 0.1 mg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry (FC/FACS), Functional Assays (FN) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Bovine CD18, clone BAQ30A, recognizes bovine CD18 also known as ITGB2 or integrin beta-2. CD18 is a receptor for ICAM1, ICAM2, ICAM3, and ICAM4. It recognizes the G-P-R motif in the fibrinogen alpha chain and is involved in leukocyte adhesion as well as transmigration of T cells and neutrophils. Different from other organisms, the signal peptide of ruminant CD18, the beta subunit, is not cleaved and remains intact on the mature CD18 molecule, leukotoxin from Pasteurella haemolytica binds to the intact signal peptide on ruminant leukocytes causing acute inflammation and lung damage (Shanthalingam et al. 2016). Holstein cattle harbor a mutation in CD18 causing bovine leukocyte adhesion deficiency (BLAD) syndrome (Kehrli et al. 1992 |
| Immunogen | Immunogen: Cells from multiple species. Buffer Solution: Serum free tissue culture medium containing proprietary protein free supplement with 0.09% Sodium Azide (NaN3) |
| Other Names | [CD18], [ITGB2; ITGB2; CD18; CD18] |
| Gene, Accession # | [ITGB2], Gene ID: 281877, NCBI: P32592.1, UniProt: P32592 |
| Catalog # | MBS225389 |
| Price | $320 |
| Order / More Info | Bovine CD18 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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