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Antigenic Specificity | NUDT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NUDT1 protein. Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode dist |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human NUDT1. |
Other Names | [MTH1] |
Gene, Accession # | [NUDT1], Gene ID: 4521, NCBI: NP_002443.3, UniProt: P36639 |
Catalog # | MBS9403464 |
Price | $255 |
Order / More Info | NUDT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |