Edit |   |
---|---|
Antigenic Specificity | PTPN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII-and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 281-435 of human PTPN1 (NP 002818.1). |
Other Names | [PTP1B] |
Gene, Accession # | [PTPN1], Gene ID: 5770, NCBI: NP_002818.1, UniProt: P18031 |
Catalog # | MBS8544465 |
Price | $280 |
Order / More Info | PTPN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |