CASP10 (Center), 164-192 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CASP10 (Center), 164-192 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CASP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the Central region of human CASP10. CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. |
| Immunogen | n/a |
| Other Names | [Caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; Caspase-10 subunit p23/17; Caspase-10 subunit p12; CASP10; MCH4] |
| Gene, Accession # | [CASP10], Gene ID: 843, NCBI: NP_001193453.1, UniProt: Q92851 |
| Catalog # | MBS9206887 |
| Price | $165, $370 |
| Order / More Info | CASP10 (Center), 164-192 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lan,Q., Morton,L.M. Blood 114 (2), 264-267 (2009) Kim,Y.R., Kim,K.M. Hum. Pathol. 40 (6), 868-871 (2009) Lisa-Santamaria,P. Biochim. Biophys. Acta 1793 (3), 561-571 (2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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