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Antigenic Specificity | CARD9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CARD9 antibody detects endogenous levels of total CARD9. Function: Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is at the crossroads of ITAM-tyrosine kinase and the Toll-like receptors (TLR) and NOD2 signaling pathways. Probably controls various innate immune response pathways depending on the intracellular pathogen. In response to L.monocytogenes infection, acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases (MAPK) without activating NF-kappa-B. Also involved in activation of myeloid cells via classical ITAM-associated receptors and TLR: required for TLR-mediated activation of MAPK, while |
Immunogen | Immunogen: A synthesized peptide derived from human CARD9 Subcellular Location: Cytoplasm. Tissue Specificity: Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Dog, Chicken Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (90%) |
Other Names | [CANDF2; CARD9; CARD9_HUMAN; Caspase recruitment domain family member 9; Caspase recruitment domain-containing protein 9; hCARD9] |
Gene, Accession # | [CARD9], Gene ID: 64170, NCBI: NP_434700.2, UniProt: Q9H257 |
Catalog # | MBS9608757 |
Price | $240, $280 |
Order / More Info | CARD9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |