SMAD6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySMAD6
Clone[5H3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionAntagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions. Tissue specificity: Ubiquitous in various organs, with higher levels in lung. Isoform B is up-regulated in diseased heart tissue.
ImmunogenImmunogen: Purified recombinant fragment of human SMAD6 expressed in E. Coli.
Other Names[MADH6; MADH7; HsT17432; SMAD6]
Gene, Accession #[SMAD6], Gene ID: 4091, NCBI: O43541.2, UniProt: O43541
Catalog #MBS8538675
Price$280
Order / More InfoSMAD6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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