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Antigenic Specificity | Mouse CD11b |
Clone | monoclonal |
Host Species | n/a |
Reactive Species | mouse, human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), CyTOF Label-Ready |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Anti-Mouse CD11b Antibody (M1/70) specifically binds to the mouse CD11b. CD11b (integrin alphaM glycoprotein) is a 170 kDa type 1 transmembrane glycoprotein which associates non-convalently with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen, and heparin. CD11b (Mac-1) is expressed on the surface of myeloid-derived dendritic cells, tissue macrophages, NK cells, microglia, granulocytes, monocytes, and subsets of T and B cells (for instance, B-1 B lymphocytes). CD11b has been used as a marker to distinguish naive and memory CD8 T cells. It has been reported that M1/70 blocks cell adherence and C3bi binding. M1/70 is found to be cross-reactive to human CD11b expressed |
Immunogen | n/a |
Other Names | [Mouse CD11b], [Itgam; Itgam; CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik] |
Gene, Accession # | [CD11b], Gene ID: 16409, NCBI: ABK96806.1 |
Catalog # | MBS417787 |
Price | $175 |
Order / More Info | Mouse CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |