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Antigenic Specificity | Human CD123 |
Clone | [6H6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD123 is the 70 kD transmembrane alpha chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common beta chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the beta chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |
Immunogen | n/a |
Other Names | [Human CD123; IL-3Ralpha; IL-3 Receptor alpha] |
Gene, Accession # | [CD123], Gene ID: 3563, NCBI: NP_001254642.1, UniProt: P26951 |
Catalog # | MBS2553989 |
Price | $90, $165 |
Order / More Info | Human CD123 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Miyajima A, et al. 1993. Blood 82:1960. |