Human 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca2+ mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation. |
| Immunogen | Immunogen: Recombinant human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 protein(1-762AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30830 / sc-30063 |
| Other Names | [hPLCD4; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4; PLCD4], [PLCD4; PLCD4; hPLCD4; PLC-delta-4] |
| Gene, Accession # | [PLCD4], Gene ID: 84812, NCBI: NP_116115.1, UniProt: Q9BRC7 |
| Catalog # | MBS1495166 |
| Price | $160, $235 |
| Order / More Info | Human 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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