Mouse SLAMF7/CRACC Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse SLAMF7/CRACC |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-cell lines. Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM), which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A), it activates NK cells in the absence of a functional SAP. CS1 is a self ligand and homophilic interaction of CS1 regulates NK cell cytolytic activity. CRACC positively regulated natural killer cell functions |
| Immunogen | Immunogen: Recombinant Mouse SLAMF7 protein Buffer: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SLAMF7 extracellular domain (rM SLAMF7; NP 653122.2; Met 1-Gly 224). |
| Other Names | [SLAM family member 7 isoform i; SLAM family member 7; SLAM family member 7; SLAM family member 7; CD2 subset 1; CD2-like receptor-activating cytotoxic cells; CRACC; Membrane protein FOAP-12; Novel Ly9; Protein 19A; CD_antigen: CD319] |
| Gene, Accession # | [SLAMF7/CRACC ], Gene ID: 57823 |
| Catalog # | MBS2544513 |
| Price | $215, $330, $500 |
| Order / More Info | Mouse SLAMF7/CRACC Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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