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Antigenic Specificity | (Mouse) Smad3 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Smad3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 157-191 amino acids from the Central region of Mouse Smad3. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocyt |
Immunogen | n/a |
Other Names | [Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; mMad3; SMAD family member 3; SMAD 3; Smad3; Smad3; Madh3] |
Gene, Accession # | [Smad3], Gene ID: 17127, NCBI: NP_058049.3, UniProt: Q8BUN5 |
Catalog # | MBS9214451 |
Price | $165, $370 |
Order / More Info | (Mouse) Smad3 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kano K.,et al.J. Vet. Med. Sci. 61:213-219(1999). Yang X.,et al.Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases. Carninci P.,et al.Science 309:1559-1563(2005). Liu X.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:10669-10674(1997). Ashcroft G.S.,et al.Nat. Cell Biol. 1:260-266(1999). |