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Antigenic Specificity | FFGV |
Clone | [BC-14] |
Host Species | Mouse |
Reactive Species | human, rat, guinea pig, horse, porcine |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 0.1 mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the N-terminal neoepitope sequence (FFGV.) generated at the ``MMP cleavage site'' after MMP catabolism in the interglobular domain of aggrecan between amino acids.PEN341 and 342FFG. (Human sequence enumeration). Aggrecan monoclonal antibody to N-terminal neoepitope FFGV (mouse, clone BC14). This fragment is rapidly released from the tissue when MMP catabolism of aggrecan occurs and has been identified in synovial fluid samples from patients with degenerative joint diseases. Overview: Proteoglycans are categoried depending upon the nature of their glycosaminoglycan chains (chondroitin sulfate, dermatan sulfate, heparan sulphate and keratan sullfate) as well as characterized by size. Aggrecan is a large aggregating proteoglyca |
Immunogen | Immunogen: Synthetic peptide: FFGVGGE. Myeloma: x63-Ag8.653. Light Chain Type: kappa |
Other Names | [Aggrecan, N-terminal neoepitope FFGV], [ACAN; ACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP; AGC1; CSPG1; MSK16; CSPCP] |
Gene, Accession # | Gene ID: 176, NCBI: AAH36445.1, UniProt: P16112 |
Catalog # | MBS442016 |
Price | $435 |
Order / More Info | FFGV Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |