Edit |   |
---|---|
Antigenic Specificity | CNOT7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of CNOT7 in human; mouse and rat. Has 3'-5' poly (A) exoribonuclease activity for synthetic poly (A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation; miRNA-mediated repression; translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with |
Immunogen | Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CNOT7 |
Other Names | [CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1; Caf1a], [CNOT7; CAF1; CAF-1] |
Gene, Accession # | [CNOT7], Gene ID: 29883, NCBI: NP_001309016.1, UniProt: Q9UIV1 |
Catalog # | MBS846113 |
Price | $345 |
Order / More Info | CNOT7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |