CNOT7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCNOT7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB); Immunohistochemistry (IHC)
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DescriptionPolyclonal antibody to detect endogenous levels of CNOT7 in human; mouse and rat. Has 3'-5' poly (A) exoribonuclease activity for synthetic poly (A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation; miRNA-mediated repression; translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with
ImmunogenImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CNOT7
Other Names[CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1; Caf1a], [CNOT7; CAF1; CAF-1]
Gene, Accession #[CNOT7], Gene ID: 29883, NCBI: NP_001309016.1, UniProt: Q9UIV1
Catalog #MBS846113
Price$345
Order / More InfoCNOT7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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