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Antigenic Specificity | NCF2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NCF2 protein. The phagocytic NADPH oxidase is a multiprotein enzyme that catalyzes the reduction of oxygen to superoxide in response to pathogenic invasion. The NADPH oxidase consists of 6 subunits, including the membrane-bound p91 phox and p22 phox heterodimers (also known as cytochrome b558), the cytosolic complex of p40phox, p47phox and p67phox, and the small GTPase Rac2. Activation of NADPH oxidase is initiated by cytosolic complex phosphorylation, which induces a conformational change that leads to the translocation of the cytosolic complex to the membrane and formation of an active enzyme with cytochrome b558 (1). Defects in p47phox, often resulting from recombination between p47phox and |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human NCF2. |
Other Names | [NCF2; FLJ93058; NCF-2; NOXA2; P67-PHOX] |
Gene, Accession # | [NCF2], Gene ID: 4688, NCBI: NP_000424.2, UniProt: P19878 |
Catalog # | MBS9403338 |
Price | $255 |
Order / More Info | NCF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |