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Antigenic Specificity | CCNB1IP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CCNB1IP1 antibody detects endogenous levels of total CCNB1IP1. Function: Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpressi |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus Tissue Specificity: Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (82%), Bovine (91%), Horse (82%), Sheep (91%), Dog (91%) |
Other Names | [C14orf18; CCNB1IP1; Chromosome 14 open reading frame 18; CIP1_HUMAN; Cyclin B1 interacting protein 1; cyclin B1 interacting protein 1, E3 ubiquitin protein ligase; Cyclin-B1-interacting protein 1; E3 ubiquitin-protein ligase CCNB1IP1; Enhancer of invasion 10; Gm288; HEI10; Human enhancer of invasion 10; mei4] |
Gene, Accession # | [CCNB1IP1], Gene ID: 57820, NCBI: NP_067001.3, UniProt: Q9NPC3 |
Catalog # | MBS9605472 |
Price | $240, $280 |
Order / More Info | CCNB1IP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |