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Antigenic Specificity | INSRR (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This INSRR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 668-702 amino acids from the Central region of human INSRR. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. |
Immunogen | n/a |
Other Names | [Insulin receptor-related protein; IRR; IR-related receptor; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; INSRR; IRR] |
Gene, Accession # | [INSRR], Gene ID: 3645, NCBI: NP_055030.1, UniProt: P14616 |
Catalog # | MBS9208916 |
Price | $165, $370 |
Order / More Info | INSRR (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Haenze J.,et al.Horm. Metab. Res. 31:77-79(1999). Gregory S.G.,et al.Nature 441:315-321(2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Shier P.,et al.J. Biol. Chem. 264:14605-14608(1989). Greenman C.,et al.Nature 446:153-158(2007). |