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Antigenic Specificity | Neurofilament 160 kD |
Clone | [RNF406] |
Host Species | Mouse |
Reactive Species | guinea pig, hamster, human, monkey, rabbit, Xenopus |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RNF406 reacts exclusively with the phosphorylated isoform of the160 kD neurofilament protein. RNF406 is suitable for immunoblotting and immunohistochemistry on frozen and paraffin-embedded tissues. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble. All three NF proteins can be detected by immunoh |
Immunogen | Source Note: RNF406 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 Mouse myeloma cells with spleen cells from a Mouse immunized with a neurofilament prepaRation of calf brain tissue. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS570174 |
Price | $415 |
Order / More Info | Neurofilament 160 kD Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. No references available |