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Antigenic Specificity | ADRB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ADRB1 antibody detects endogenous levels of total ADRB1. Function: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha-and cAMP-mediated signaling.Subunit Structure: Interacts (via C-terminus PDZ motif) with RAPGEF2; the interaction is direct. Interacts with GOPC, MAGI3 and DLG4.Post-translational Modifications: Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.Similarity: The PDZ domain-binding motif mediates competitive interactions with GOPC, MAGI3 and |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. |
Other Names | [ADR B1; ADRB 1; ADRB1; ADRB1_HUMAN; ADRB1R; Adrenergic beta 1 receptor; Adrenoceptor beta 1; B1AR; Beta 1 adrenoceptor; Beta 1 adrenoreceptor; Beta-1 adrenergic receptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR; RHR] |
Gene, Accession # | [ADRB1], Gene ID: 153, NCBI: NP_000675.1, UniProt: P08588 |
Catalog # | MBS9604223 |
Price | $240, $280 |
Order / More Info | ADRB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |