Bak (BH3 Domain Specific), 56-91 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Bak (BH3 Domain Specific), 56-91 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Bak antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-91 amino acids from human Bak. BAK belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAK localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
| Immunogen | n/a |
| Other Names | [Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7; BAK1; BAK; BCL2L7; CDN1] |
| Gene, Accession # | [BAK1], Gene ID: 578, NCBI: NP_001179.1, UniProt: Q16611 |
| Catalog # | MBS9201878 |
| Price | $165, $370 |
| Order / More Info | Bak (BH3 Domain Specific), 56-91 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cartron, P.F., et al., Mol. Cell. Biol. 23(13):4701-4712 (2003). Mikhailov, V., et al., J. Biol. Chem. 278(7):5367-5376 (2003). Werner, A.B., et al., J. Biol. Chem. 277(25):22781-22788 (2002). Bellosillo, B., et al., Blood 100(5):1810-1816 (2002). Grutkoski, P.S., et al., Shock 17(1):47-54 (2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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