FLT3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FLT3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: At least three isoforms of FLT3 are known to exist; this antibody will detect all isoforms. FLT3 Antibody: FLT3 is a member of the class III receptor tyrosine kinase family and its internal tandem duplication (ITD) is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. It is a membrane bound glycosylated protein that is expressed primarily in early hematopoietic progenitor cells. Upon binding its ligand FL, FLT3 activates multiple signaling pathways including the PI3K/Akt and Ras/MEK/MAPK pathways. In cells expressing FLT3-ITD, these pathways are constitutively on, resulting in abnormal cell growth and anti-apoptotic activity. |
| Immunogen | Immunogen: FLT3 antibody was raised against an 18 amino acid synthetic peptide near the center of human FLT3. Buffer: FLT3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [FLT3; FLK2; STK1; CD135; FLK-2; FLK2; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; fms-related tyrosine kinase 3], [FLT3; FLT3; FLK2; STK1; CD135; FLK-2; CD135; FLK2; STK1; FLK-2; FLT-3; STK-1] |
| Gene, Accession # | [FLT3], Gene ID: 2322, NCBI: NP_004110, UniProt: P36888 |
| Catalog # | MBS153583 |
| Price | $375 |
| Order / More Info | FLT3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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