Human Serglycin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Serglycin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionPlays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of someproteases in both connective tissue and mucosal mast cells and for storage ofgranzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase inazurophil granules of neutrophils. Mediates processing of MMP2. Plays a role incytotoxic cell granule-mediated apoptosis by forming a complex with granzymeB which is delivered to cells by perforin to induce apoptosis. Regulates thesecretion of TNF-alpha and may also regulate protease secretion. Inhibits bonemineralization.
ImmunogenImmunogen: Recombinant human Serglycin protein(28-158aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28007 / sc-28008 / sc-292311
Other Names[Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein), SRGN, PRG, PRG1], [SRGN; SRGN; PPG; PRG; PRG1; PRG; PRG1; P.PG]
Gene, Accession #[SRGN], Gene ID: 5552, NCBI: NP_002718.2, UniProt: P10124
Catalog #MBS1495765
Price$120, $160
Order / More InfoHuman Serglycin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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