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Antigenic Specificity | Human Serglycin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of someproteases in both connective tissue and mucosal mast cells and for storage ofgranzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase inazurophil granules of neutrophils. Mediates processing of MMP2. Plays a role incytotoxic cell granule-mediated apoptosis by forming a complex with granzymeB which is delivered to cells by perforin to induce apoptosis. Regulates thesecretion of TNF-alpha and may also regulate protease secretion. Inhibits bonemineralization. |
Immunogen | Immunogen: Recombinant human Serglycin protein(28-158aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28007 / sc-28008 / sc-292311 |
Other Names | [Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein), SRGN, PRG, PRG1], [SRGN; SRGN; PPG; PRG; PRG1; PRG; PRG1; P.PG] |
Gene, Accession # | [SRGN], Gene ID: 5552, NCBI: NP_002718.2, UniProt: P10124 |
Catalog # | MBS1495765 |
Price | $120, $160 |
Order / More Info | Human Serglycin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |