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Antigenic Specificity | KMT5B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3. |
Immunogen | Immunogen: Recombinant Human Histone-lysine N-methyltransferase KMT5B protein (100-150AA) |
Other Names | [Histone-lysine N-methyltransferase KMT5BCurated; Lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B; KMT5B] |
Gene, Accession # | [KMT5B], Gene ID: 51111, NCBI: NP_001287838.1, UniProt: Q4FZB7 |
Catalog # | MBS7105265 |
Price | $160, $235 |
Order / More Info | KMT5B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |