CFH (Center), 751-780 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CFH (Center), 751-780 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.287 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH. This gene is a member of the Regulator of ComplementActivation (RCA) gene cluster and encodes a protein with twentyshort concensus repeat (SCR) domains. This protein is secreted intothe bloodstream and has an essential role in the regulation ofcomplement activation, restricting this innate defense mechanism tomicrobial infections. Mutations in this gene have been associatedwith hemolytic-uremic syndrome (HUS) and chronic hypocomplementemicnephropathy. Alternate transcriptional splice variants, encodingdifferent isoforms, have been characterized. |
| Immunogen | n/a |
| Other Names | [Complement factor H; H factor 1; CFH; HF; HF1; HF2] |
| Gene, Accession # | [CFH], Gene ID: 3075, NCBI: NP_000177.2, UniProt: P08603 |
| Catalog # | MBS9202326 |
| Price | $165, $370 |
| Order / More Info | CFH (Center), 751-780 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Dieterich, R., et al. Infect. Immun. 78(11):4467-4476(2010) Sofat, R., et al. Atherosclerosis 213(1):184-190(2010) Davila, S., et al. Nat. Genet. 42(9):772-776(2010) Scambi, C., et al. PLoS ONE 5 (8), E12162 (2010) : Bunkenborg, J., et al. Proteomics 4(2):454-465(2004) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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