Edit |   |
---|---|
Antigenic Specificity | Phospho-PDGFRA-Y754 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secret |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y754 of human PDGFRA |
Other Names | [CD140A; PDGFR2; PDGFR-2] |
Gene, Accession # | [PDGFRA], Gene ID: 5156, NCBI: NP_006197.1, UniProt: P16234 |
Catalog # | MBS8550656 |
Price | $280 |
Order / More Info | Phospho-PDGFRA-Y754 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |