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Antigenic Specificity | Human CD146 |
Clone | [OJ79c] |
Host Species | Mouse |
Reactive Species | porcine,dog; |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistochemistry-Frozen (IHC-Fr), ELISA (EIA), Flow cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD146 antibody, clone OJ79c recognizes human Cell surface glycoprotein MUC18, also known as CD146, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule or S-endo 1 endothelial-associated antigen. CD146 is a 646 amino acid single pass type 1 transmembrane glycoprotein with a calculated molecular mass of ~72 kDa. However due to extensive N-linked glycosylation CD146 migrates in polyacrylamide gels with an apparent molecular mass of ~:118 kDa. CD146 is a member of the immunoglobulin superfamily bearing 2 V-type Ig-like and 3 C-type Ig-like domains. CD146 is expressed by all endothelial cells and by melanoma cells and appears to act as an adhesion molecule (UniProt: P43121). Expression in melanoma may be linked |
Immunogen | Immunogen: Recombinant human MUC18 (D1-D5) Fc protein. Fusion Partners: Spleen cells from immunized mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line. Histology Positive Control Tissue: Melanoma |
Other Names | [cell surface glycoprotein MUC18; Cell surface glycoprotein MUC18; cell surface glycoprotein MUC18; Gicerin; S-endo 1 endothelial-associated antigen; cell surface glycoprotein P1H12; melanoma adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; melanoma cell adhesion molecule; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD_antigen: CD146], [MCAM; MCAM; CD146; MUC18; MUC18] |
Gene, Accession # | [CD146], Gene ID: 4162, NCBI: NP_006491.2, UniProt: P43121 |
Catalog # | MBS212519 |
Price | $430 |
Order / More Info | Human CD146 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |